Laboratorio de Ictiofisiología y Acuicultura

El laboratorio fue establecido en el año 2001 y si bien estudia fundamentalmente la fisiologia de peces y la acuicultura del pejerrey, trabaja también, con un enfoque comparativo, en fisiología de la reproducción y diferenciación sexual en otros grupos de vertebrados. Las líneas de trabajo no sólo se relacionan con experimentos de laboratorio sino también en ecofisiología de la reproducción en peces y estresores ambientales naturales y de origen antrópico.

Publicaciones

Montaner, A.D.; Park, M.; Fischer, W.H.; Craig, A.G.; Chang, J.P.; Somoza, G.M.; Rivier, J.E. & Sherwood, N.M. Primary structure of a novel gonadotropin-releasing hormone (GnRH) variant in the brain of pejerrey (Odontesthes bonariensis). Endocrinology 142: 1453-1460. 2001.

Miranda, L.A.; Strüssmann, C & Somoza, GM. Immunocytochemical identification of GTH1 and GTH2 cells during the temperature-sensitive period for sex determination in pejerrey, Odontesthes bonariensis. General and Comparative Endocrinology 124: 45-52. 2001.

Miranda, L.A.; Escaray, R.U.; Bustingorry, J.F. & Somoza, G.M.. Effects of photoperiod and human chorionic gonadotropin (hCG) administration on spermiation in pejerrey Odontesthes bonariensis. Revista Argentina de Producción Animal 21: 95-105. 2001.

Montaner, A.D.; Miranda, L.A.; Vizziano, D; López, A., Okuzawa, K.A. & Somoza, G.M.. Gonadotropin-releasing hormone (GnRH) molecular forms in two perciform fishes: Micropogonias furnieri and Pagrus pagrus. Fish Physiology and Biochemistry 21: 95-105. 2001.

Miranda, L.A.; Strobl-Mazzulla, P.A. & Somoza, G.M. Ontogenetic development and neuroanatomical localization of Growth Hormone-Releasing Hormone (GHRH) in the Brain and Pituitary Gland of Pejerrey Odontesthes bonariensis. Journal of Developmental Neurosciences 20: 503-510. 2002.

Somoza, G.M.; Lescheid, D.; Miranda, L.A.; Lo Nostro, F.L.; Magliulo-Cepriano, L.; Montaner, A.D.; Schreibman, M.P.; Rivier, J.E. & Sherwood, N.M. Expression of pejerrey gonadotropin-releasing hormone (pjGnRH) in three orders of fish. Biology of Reproduction 67:1864-1871. 2002.

Somoza, G.M.; Miranda, L.A.; Strobl-Mazzulla, P.H. & Guilgur, L.G. Gonadotropin-releasing hormone (GnRH): from fish to mammalian brains. Cellular and Molecular Neurobiology 22: 589-609. 2002.

Miranda, L.A.; Strobl-Mazzulla, P.H.; Strüssmann, C.A.; Parhar, I.S. & Somoza, G.M. Gonadotropin-releasing hormone neuronal development during the sensitive period of temperature sex determination in the pejerrey fish, Odontesthes bonariensis. General and Comparative Endocrinology 132: 444-453. 2003.

Miranda, L.A.; Guilgur, L.G. & Somoza, G.M. Molecular cloning of cDNAs encoding FSH-β and LH-β subunits in the pejerrey fish, Odontesthes bonariensis. Fish Physiology and Biochemistry 28: 101-102. 2003.

Guilgur, L.G.; Miranda, L.A. & Somoza, G.M. Characterization of three GnRH cDNA sequences in the pejerrey fish Odontesthes bonariensis. Fish Physiology and Biochemistry 28: 39-40. 2003.

Fernandino, J.L.; Guilgur, L.G.; Strobl-Mazzulla, P.H. & Somoza, G.M. Molecular cloning of SOX9, DMRT1 and SF1 cDNA partial sequences in the pejerrey fish Odontesthes bonaerensis (Atheriniformes). Fish Physiology and Biochemistry 28: 145-146. 2003.

Strobl-Mazzulla, P.H.; López, G.C.; Miranda, L.A. & Somoza, G.M. Neuroanatomical distribution and partial sequence of cDNA encoding brain cytochrome p450 aromatase (p450aromb) in pejerrey Odontesthes bonariensis. Fish Physiology and Biochemistry 28: 51-52. 2003.

Strüssmann, C.A.; Karube, M.; Miranda, L.A.; Patiño, R.; Somoza, G.M.; Uchida, D. & Yamashita, M. Methods of sex control in fishes and an overview of novel hypotheses concerning the mechanisms of sex differentiation. En: «Fish genetics and aquaculture biotechnology«. Editado por Pandian, T.J.; Strüssmann, C.A. & Marian, M.P. Oxford & IBH Publishing/Science Publishers, New Delhi, India/Enfield, USA. pp. 65-79. 2004.

Moncaut, N.P.; Somoza, G.M.; Power, D.M. & Canário, A.V.M. Five gonadotrophin-releasing hormone receptors in a teleost fish: Isolation, tissue distribution and phylogenetic relationships. Journal of Molecular Endocrinology 34: 767-779. 2005.

Strobl-Mazzulla, P.H.; Moncaut, N.P.; López, G.C.; Miranda, L.A.; Canário, A.V.M. & Somoza, G.M. Brain aromatase from pejerrey fish (Odontesthes bonariensis): cDNA cloning, tissue expression, and immunohistochemical localization. General and Comparative Endocrinology 143: 21-32. 2005.

Sorianello, E.M.; Fernandez, M.O.; Catalano, P.N.; Mongiat, L.A.; Somoza, G.M.; Libertun, C. & Lux-Lantos, V.A. Differential gonadotropin releasing hormone (GnRH) expression, autoregulation and effects in two models of rat luteinized ovarian cells. Life Sciences 77: 2141-2155. 2005.

Miranda, L.A.; Cassará, M.C & Somoza, G.M. Increase of milt production by hormonal treatment in the pejerrey fish Odontesthes bonariensis. Aquaculture Research 36: 1473-1479, 2005.

Sciara, A.A.; Rubiolo, J.A.; Somoza, G.M. & Arranz, S.E. Molecular cloning, expression and immunological characterization of pejerrey (Odontesthes bonariensis) growth hormone. Comparative Biochemistry and Physiology 142C: 284-292. 2006.

Miranda, L.A.; Berasain, G.E.; Velasco, C.A.M.; Shirojo, Y. & Somoza, G.M. Natural spawning and intensive culture of pejerrey Odontesthes bonariensis juveniles. Biocell 30: 157-162. 2006.

Somoza, G.M.; Miranda, L.A.; Guilgur, L.G. & Strobl-Mazzulla, P.H. Characterization of the brain-pituitary axis in pejerrey Odontesthes bonariensis. Biocell 30: 89-95. 2006.

Guilgur, L.G.; Moncaut, N.P.; Canário, A.V.M. & Somoza, G.M. Evolution of GnRH ligands and receptors in Gnathostomata. Comparative Biochemistry and Physiology 144: 272-283. 2006.

Copello, S., Quintana, F.R. & Somoza, G.M. Sex determination and sexual size dimorphism in the Southern Giant Petrel (Macronectes giganteus). Emu 106: 141-146. 2006.

Mongiat, L.; Fernández, M.O.; Lux-Lantos, V.A.R.; Guilgur, L.G.; Somoza, G.M. & Libertun, C. Experimental data supporting the expression of the highly conserved GnRH-II in the brain and pituitary gland of rats. Regulatory Peptides 136: 50-57. 2006.

Fernandino, J.I.; Guilgur, L.G. & Somoza, G.M. Dmrt1 expression analysis during spermatogenesis in pejerrey, Odontesthes bonariensis. Fish Physiology and Biochemistry 32: 231-240. 2006.

Kah, O.; Lethimonier, C.; Somoza, G.M.; Guilgur, L.; Vaillant, C.; Lareyre, J.J. GnRH and GnRH receptors in Metazoa: A historical, comparative and evolutive perspective. General and Comparative Endocrinology 153: 346-364. 2007.

Guilgur, L.G.; Ortí, G.; Strobl-Mazzulla, P.H.; Fernandino, J.I.; Miranda, L.A. & Somoza, G.M. Characterization of the cDNAs encoding three GnRH forms in the pejerrey fish Odontesthes bonariensis (Atheriniformes) and the evolution of GnRH precursors. Journal of Molecular Evolution 64: 614-627. 2007.

Miranda, L.A.; Strüssmann, C.A.; Guilgur, L.G.; Strobl-Mazzulla, P.H. & Somoza, G.M. Cloning of FSH-β, LH- β and glycoprotein hormone α subunits in pejerrey fish Odontesthes bonariensis. Expression profile and relationship with GnRHs expression and plasma sex steroid levels in male fish. Journal of Fish Biology 71: 1571–1589. 2007.

Karube, M.; Fernandino, J.I.; Strobl-Mazzulla, P.H.; Strüssmann, C.A.; Yoshizaki, G.; Somoza, G.M. & Patiño, R. Characterization and expression profile of the ovarian cytochrome p-450 aromatase (cyp19a1) gene during the thermolabile sex determination period in pejerrey, Odontesthes bonariensis. Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 307: 625-636. 2007.

Awruch, C.A.; Lo Nostro, F.L.; Somoza, G.M. & Di Giácomo, E. Reproductive biology of the angular angel shark, Squatina guggenheim (Chondrichthyes: Squatinidae) of Patagonia (Argentina, southwestern Atlantic). Ciencias Marinas 34: 17-28. 2008.

Somoza, G.M.; Miranda, L.A.; Berasain, G.E.; Colautti, D.; Remes Lenicov, M. & Strüssmann, C.A. Historical aspects, current status, and prospects of pejerrey aquaculture in South America. Aquaculture Research 39: 784-793. 2008.

Sciara, A.A.; Somoza, G.M. & Arranz, S.E. Insulin-like growth factor I of pejerrey, Odontesthes bonariensis: cDNA characterization, tissue distribution and expression profiles after growth hormone administration. Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 309: 407-418. 2008.

Strobl-Mazzulla, P.H.; Lethimonier, C.; Gueguen, M.M.; Karube, M.; Fernandino, J.I.; Yoshizaki, G.; Patiño, R.; Strüssmann, C.A.; Kah, O. & Somoza, G.M. Brain aromatase (Cyp19A2) and estrogen receptors, in larvae and adult pejerrey fish Odontesthes bonariensis. Neuroanatomical and functional relations. General and Comparative Endocrinology 158: 191-201. 2008.

Guilgur, L.G. & Somoza, G.M. Cloning, characterization and tissue distribution expression pattern of two GnRH receptors in pejerrey. Cybium 32: 43-44. 2008.

Blasco, M.; Somoza, G.M. & Vizziano, D. Androgen synthesis in the silverside Odontesthes bonariensis. Cybium 32: 86. 2008.

Fernandino, J.I.; Hattori, R.S.; Strobl-Mazzulla, P.H.; Strüssmann, C.A. & Somoza, G.M. Expression of dmrt1 and ovarian aromatase during the sex differentiation period in pejerrey, Odontesthes bonariensis. Cybium 32: 93-94. 2008.

Hattori, R.S.; Fernandino, J.I.; Strüssmann, C.A.; Somoza, G.M.; Yokota, M. & Watanabe, S. Characterization and expression profiles of DMRT1, AMH, SF1 and P45aro genes during gonadal sex differentiation in Patagonian pejerrey Odontesthes hatcheri. Cybium 32: 95-96. 2008.

Strobl-Mazzulla, P.H.; Fernandino, J.I.; Guilgur, L.G.; Núñez, A.; Strüssmann, C.; Pellegrini, E.; Kah, O. & Somoza, G.M. Relationship between brain cell proliferation and aromatase expression during thermolabile sex determination/differentiation period in pejerrey fish. Cybium 32: 109-110. 2008.

Izaguirre M.F.; García-Sancho, M.N.; Miranda, L.A.; Tomas, J. & Casco, V.H. Influence of thyroid hormones on the expression of cell adhesion molecules in the developing kidney of Bufo arenarum tadpoles. Brazilian Journal of Biology 68: 561-569. 2008.

Soria, F.N.; Strüssmann, C.A. & Miranda, L.A. high water temperatures impair the reproductive ability of the pejerrey fish Odontesthes bonariensis: Effects on the hypophyseal-gonadal axis. Physiological and Biochemical Zoology 81: 898-905. 2008.

Fernandino, J.I.; Hattori, R.S.; Kimura, H.; Strüssmann, C.A. & Somoza, G.M. Expression profile and estrogenic regulation of anti-Müllerian hormone during gonadal development in pejerrey Odontesthes bonariensis, a teleost fish with strong temperature-dependent sex determination. Developmental Dynamics 237: 3192-3199. 2008.

Quintana, F.R.; López, G.C. & Somoza, G.M. A cheap and quick method for DNA-based sexing of birds. Waterbirds 31: 485-488. 2008.

Fernandino, J.I.; Hattori, R.S.; Shinoda, T.; Kimura, H.; Strobl-Mazzulla, P.H.; Strüssmann, C.A. & Somoza, G.M. Dimorphic expression of dmrt1 and cyp19a1 (ovarian aromatase) during early gonadal development in pejerrey, Odontesthes bonariensis. Sexual Development 2: 316-324. 2008.

Miranda, L.A.; Strüssmann, C.A. & Somoza, G.M. Effects of light and temperature conditions on the expression of GnRH and GtH genes and plasma steroids levels in Odontesthes bonariensis females. Fish Physiology and Biochemistry 35: 101-108. 2009.

Guilgur, L.G.; Strüssmann, C.A. & Somoza, G.M. mRNA expression of GnRH variants and receptors in the brain, pituitary and ovaries of pejerrey (Odontesthes bonariensis) in relation to the reproductive status. Fish Physiology and Biochemistry 35: 157-166. 2009.

Blasco, M.; Carriquiriborde, P.; Marino, D.; Ronco, A.E. & Somoza, G.M. A quantitative HPLC-MS method for the simultaneous determination of testosterone, 11-ketotestosterone and 11-β hydroxy-androstenedione in fish serum. Journal of Chromatography B 877: 1509-1515. 2009.

Zhao, E.; Basak, A.; Wong, A.O.L.; Ko, W.; Chen, A.; López, G.C.; Grey, C.L.; Canosa, L.F.; Somoza, G.M.; Chang, J.P. & Trudeau, V.L. The Secretogranin II-derived peptide secretoneurin stimulates Luteinizing Hormone secretion from gonadotrophs. Endocrinology 150: 2273-2282. 2009.

Carriquiriborde, P.; Díaz, J.; López, G.C.; Ronco, A.E. & Somoza, G.M. Effects of cypermethrin chronic exposure and water temperature on survival, growth, sex differentiation, and gonadal developmental stages of Odontesthes bonariensis (Teleostei). Chemosphere 76: 374-380. 2009.

Hattori, R.S.; Fernandino, J.I.; Kishii, A.; Kimura, H.; Kinno, T.; Oura, M.; Somoza, G.M.; Yokota, M.; Strüssmann, C.A. & Watanabe, S. Cortisol-Induced Masculinization: Does thermal stress affect gonadal fate in pejerrey, a teleost fish with temperature-dependent sex determination? PLOS ONE 4(8): e6548. doi:10.1371/journal.pone.0006548. 2009.

Miranda, L.A. & Somoza, G.M. Spawning induction of pejerrey Odontesthes bonariensis in captivity by the use of sustained-release GnRHa implants. Aquaculture Research 41: 129-134. 2009.

Colautti, D.C.; García, J. & Miranda, L.A. Sistema de cultivo mixto en jaulas y estanques para el pejerrey Odontesthes bonariensis. Biología Acuática 26:47-54. 2009.

Shinoda, T.; Miranda, L.A.; Okuma, K.; Hattori, R.S.; Fernandino, J.I.; Yoshizaki, G.; Somoza, G.M. & Strüssmann, C.A. Molecular cloning and expression analysis of Fshr and Lhr in relation to Fshβ and Lhβ subunits during the period of temperature-dependent sex determination in pejerrey Odontesthes bonariensis. Molecular Reproduction and Development 77: 521-532. 2010.

Lichtenstein, G.; Elisio, M. & Miranda, L.A. (2010). Development of sperm cryopreservation techniques in pejerrey Odontesthes bonariensis. Aquaculture 306: 357-361. 2010.

Strobl-Mazzulla, P.H.; Núñez, A.; Pellegrini, E.; Gueguen, M.M.; Kah, O. & Somoza, G.M. Progenitor radial cells and neurogenesis in pejerrey fish forebrain. Brain, Behavior and Evolution 76: 20-31. 2010.

Strüssmann, C.A.; Conover, D.O.; Somoza, G.M. & Miranda, L.A. Implications of climate change for the reproductive capacity and survival of Atherinopsid fish species. Journal of Fish Biology 77: 1818-1834. 2010.

Miranda, L.A.; Chalde, T. & Elisio, M. Effects of daily water temperature fluctuations on brain-pituitray-gonad axis of pejerrey (Odontesthes bonariesnis) during its reproductive season. Indian Journal of Science and Technology 9^th ISRPF Issue 4, 38-39. 2011.

Carmanchahi, P.D.; Ovejero, R.; Marull, C.; López, G.C.; Schroeder, N.; Jahn, G.A.; Novaro, A.J. & Somoza, G.M. Physiological response of wild guanacos to capture for live shearing. Wildlife Research 38: 61-68. 2011.

Fernandino, J.I.; Popesku, J.T.; Paul-Prasanth, B.; Xiong, H-L.; Hattori, R.S.; Strüssmann, C.A.; Somoza, G.M.; Matsuda, M.; Nagahama, Y. & Trudeau, V.L. Analysis of sexually dimorphic expression of genes at early gonadogenesis of pejerrey Odontesthes bonariensis using a heterologous microarray. Sexual Development 5: 89-101. 2011.

Somoza, G.M. & Ross, L.G. Introduction to the special issue on ‘‘Development of native species for aquaculture in Latin America II’’. Aquaculture Research 42: 737. 2011.

Sciara, A.A; Vigliano, F.; Somoza, G.M. & Arranz, S.E. Muscular hypertrophy and growth promoting effects in juvenile pejerrey (Odontesthes bonariensis) after oral administration of recombinant homologous growth hormone obtained by a highly efficient refolding process. Aquaculture Research 42: 844-857. 2011.

Canosa, L.F.; López, G.C.; Scharrig, E.; LeSaux-Farmer, K.; Somoza, G.M.; Kah, O. & Trudeau, V.L. Forebrain mapping of secretoneurin-like immunoreavtivity and its colocalization with isotocin in the preoptic nucleus and pituitary gland of goldfish. Journal of Comparative Neurology 519: 3748-3765. 2011.

Chalde, T.; Fernández, D.A.; Cussac, V. & Somoza, G.M. The effect of rearing temperature in larval development of pejerrey, Odontesthes bonariensis. Morphological indicators of development. Neotropical Ichthyology 9: 747-756. 2011.

Elisio, M.; Soria, F.N.; Fernandino, J.I.; Strüssmann, C.A.; Somoza, G.M. & Miranda, L.A. Extrahypophyseal expression of gonadotropin subunits in pejerrey Odontesthes bonariensis and effects of high water temperatures on their expression. General and Comparative Endocrinology 175: 329-336. 2012.

Elisio, M.; Chalde, T. & Miranda, L.A. Effects of short periods of warm water fluctuations on reproductive endocrine axis of the pejerrey (Odontesthes bonariensis) spawning. Comparative Biochemistry and Physiology 163: 47-55. 2012.

Pérez-Sirkin, D.I., Cánepa, M.M., Fossati, M., Fernandino, J.I., Delgadín, T.,Canosa, L.F., Somoza, G.M. & Vissio, P.G. Melanin concentrating hormone (MCH) is involved in the regulation of growth hormone in Cichlasoma dimerus (Cichlidae, Teleostei). General and Comparative Endocrinology 176: 102-111. 2012.

Hattori, R.S.; Murai, Y.; Oura, M.; Masuda, S.; Majhi, S.K.; Sakamoto, T.; Fernandino, J.I.; Somoza, G.M.; Yokota, M. & Strüssmann, C.A. A Y-linked anti-Müllerian hormone duplication takes over a critical role in sex determination. Proceedings of the National Academy of Sciences of the United States of America. 109: 2955-2959. 2012.

Pérez, M.R.; Fernandino, J.I.; Carriquiriborde, P. & Somoza, G.M. Feminization and altered gonadal gene expression profile by ethynylestradiol exposure to pejerrey, Odontesthes bonariensis, a South American teleost fish. Environmental Toxicology and Chemistry 31: 941-946. 2012.

Fernandino, J.I.; Hattori, R.S.; Kishii, A.; Strüssmann, C.A. & Somoza, G.M. The cortisol and androgen pathways cross-talk in high temperature-induced masculinization: the 11β-hydroxysteroid dehydrogenase as a key enzyme. Endocrinology 153: 6003-6011. 2012.

Blasco, M.; Somoza, G.M. & Vizziano-Cantonnet, D. Presence of 11-ketotestosterone in pre-differentiated male gonads of Odontesthes bonariensis. Fish Physiology and Biochemistry39: 71-74. 2013.

Campanella, D.; Garriz, A.; Colautti, D.C.; Somoza, G.M. & Miranda, L.A. Osmotic induction marking with Alizarin Red S on pejerrey, Odontesthes bonariensis juveniles. Neotropical Ichthyology 11: 95-100. 2013.

Fernandino, J.I.; Hattori, R.S.; Strüssmann, C.A. & Somoza, G.M. Atherinopsid fishes as models for the study of temperature-dependent sex determination: physiology of gonadal sex differentiation in pejerrey Odontesthes bonariensis. En “Sexual Plasticity and Gametogenesis in Fishes”. Edited by Senthilkumaran, B. NOVA Science Publishers Inc., USA. pp. 57-71, 2013.

Somoza, G.M. & Trudeau, V.L. 7th International symposium on fish endocrinology special issue. General and Comparative Endocrinology 192: 1. 2013.

Fernandino, J.I.; Hattori, R.S.; Moreno Acosta, O.D.; Strüssmann, C.A. & Somoza, G.M. Environmental stress-induced testis differentiation: androgen as a by-product of cortisol inactivation. General and Comparative Endocrinology 192: 36-44. 2013.

Hattori, R.S.; Strüssmann, C.A.; Fernandino, J.I. & Somoza, G.M. Genotypic sex determination in teleosts: insights from the testis-determining amhy gene. General and Comparative Endocrinology 192: 55-59. 2013.

Pérez, M.R.; Pellegrini, E.; Cano-Nicolau, J.; Gueguen, M.M.; Menouer, D.; Merot, Y.; Vaillant, C.; Somoza, G.M. & Kah, O. Relationships between radial glial progenitors and 5-HT neurons in the paraventricular organ of adult zebrafish: Potential effects of serotonin on adult neurogenesis. European Journal of Neuroscience 38: 3292-3301. 2013.

Rueda, E.C.; Carriquiriborde, P.; Monzón, A.M.; Somoza, G.M. & Ortí, G. Seasonal variation in genetic population structure of sábalo (Prochilodus lineatus) in the Lower Uruguay River. Genetica 141: 401-407. 2013.

Di Giorgio, N.P.; Catalano, P.N.; López, P.V.; González, B.; Semaan, S.J.; López, G.C.; Kauffman, A.S.; Rulli, S.B.; Somoza, G.M.; Bettler, B.; Libertun, C. & Lux-Lantos, V.A. Lack of functional GABAb receptors alters Kiss1, GnRH1 and Gad1 mRNA expression in the medial basal hypothalamus at postnatal day 4. Neuroendocrinology 98: 212-223. 2013.

Miranda, L.A.; Chalde, T.; Elisio, M. & Strüssmann, C.A. Effects of global warming on fish reproductive endocrine axis with special emphasis in pejerrey Odontesthes bonariensis. General and Comparative Endocrinology 192: 45-54. 2013.

Gárriz, A. & Miranda, L.A. Ultrastructure of fresh and post thawed sperm of pejerrey Odontesthes bonariensis (Atheriniformes). Neotropical Ichthyology 11: 831-836. 2013.

Chalde, T.; Elisio, M. & Miranda, L.A. Quality of pejerrey (Odontesthes bonariensis) eggs and larvae in captivity throughout spawning season. Neotropical Ichthyology 12: 629-634. 2014.

Elisio, M.; Chalde, T.; Miranda, L.A. Endocrine regulation of pejerrey (Odontesthes bonariensis) oogenesis. Influence of environmental cues on its natural reproductive cycle. Comparative Biochemistry and Physiology 175: 102-109. 2014.

Fernandino, J.I.; Hattori, R.S.; Strüssmann, C.A.; Yamamoto, Y. & Somoza, G.M. Sex determination in fish: Odontesthes spp. (Atherinopsidae) as experimental models. Animal Reproduction 12: 24-27. 2015

Valdés, M.E.; Marino, D.J.; Wunderlin, D.A.; Somoza, G.M.; Ronco, A.E.; Carriquiriborde, P. Screening concentration of E₁, E₂ and EE₂ in sewage effluent and surface waters of the “Pampas” region and the “Río de la Plata” estuary (Argentina). Bulletin of Environmental Contamination and Toxicology 94: 29-33. 2015

González, A.; Fernandino, J.I. & Somoza, G.M. Effects of 5α-dihydrotestosterone on expression of genes related to steroidogenesis and spermatogenesis during the sex determination and differentiation periods of the pejerrey, Odontesthes bonariensis. Comparative Biochemistry and Physiology Part A 182: 1-7. 2015.

Ramallo, M.R.; Birba, A.; Honji, R.M.; Morandini, L.; Moreira, R.G.; Somoza, G.M. & Pandolfi, M. A multidisciplinary study on social status and the relationship between interindividual variation in hormone levels and agonistic behavior in a Neotropical cichlid fish. Hormones and Behavior 69: 139-151. 2015.

Iungman, J.L.; Somoza, G.M. & Piña, C.I. Are stress-related hormones involved in the temperature-dependent sex determination (TSD) of broad-snouted caiman? The South American Journal of Herpetology 10: 41-49. 2015.

Parachú Marcó, M.V.; Piña, C.I.; Somoza, G.M.; Jahn, G.A.; Pietrobon, E.O. & Iungman, J.L. Corticosterone plasma levels of embryos and hatchlings broad-snouted caiman (Caiman latirostris) incubated at different temperatures. The South American Journal of Herpetology 10: 50-57. 2015.

Carriquiriborde, P. & Somoza, G.M. Representan nuestros efluentes cloacales un riesgo para los ecosistemas acuáticos y la salud? Ciencia e Investigación 65: 72-77. 2015.

Pouso, P.; Quintana, L.; López, G.C.; Somoza, G.M.; Silva, A.C. & Trudeau, V.L. The secretogranin-II derived peptide secretoneurin modulates electric behavior in the weakly pulse type electric fish, Brachyhypopomus gauderio. General and Comparative Endocrinology 222: 158-166. 2015.

Morandini, L.; Ramallo, M.R.; Moreira, R.G.; Höcht, C.; Somoza, G.M.; Silva, A. & Pandolfi, M. Serotonergic outcome, stress and sexual steroid hormones, and growth in a South American cichlid fish fed with an L-tryptophan enriched diet. General and Comparative Endocrinology 223: 27-37. 2015.

Menéndez-Helman R.J.; Miranda, L.A. & Salibián, A. Subcellular Energy Balance of Odontesthes bonariensis Exposed to a Glyphosate-based Herbicide. Ecotoxicology and Environmental Safety 114: 157-163. 2015.

Elisio, M.; Vitale, A. & Miranda, L.A, Influence of climate variations on Chascomús shallow lake thermal conditions and its consequences on the reproductive ecology of the Argentinian Silverside (Odontesthes bonariensis – Actinopterygii, Atherinopsidae). Hydrobiologia 752: 155-166. 2015.

Berasain, G.E.; Colautti, D.C.; Remes-Lenicov, M.; Argemi, F.; Bohn, V.Y. & Miranda, L.A. Impact of water salinity on pejerrey (Odontesthes bonariensis) fisheries in Chasicó lake. Hydrobiologia 752: 167-174. 2015.

Elisio, M.; Chalde, T. & Miranda, L.A. Seasonal changes and endocrine regulation of pejerrey (Odontesthes bonariensis) spermatogenesis in the wild. General and Comparative Endocrinology 221: 236-243. 2015.

Gárriz, A.; Menéndez-Helman, R.J. & Miranda, L.A. Effects of estradiol and/or ethinylestradiol on sperm quality, fertilization, embryos and larvae survival of pejerrey fish Odontesthes bonariensis. Aquatic Toxicology 167: 191-199. 2015.

Chalde, T.; Gárriz, A.; Sánches, E.A. & Miranda, L.A. Age-related gamete quality, reproductive performance and plasma sex steroids of pejerrey (Odontesthes bonariensis) broodstocks throughout the breeding season. Aquaculture Research 47: 969-982. 2016.

Di Yorio, M.P.; Pérez-Sirkin, D.I.; Delgadín, T.H.; Shimizu, A.; Tsutsui, K.; Somoza, G.M. & Vissio, P.G. Gonadotropin-inhibitory hormone in the cichlid fish Cichlasoma dimerus: structure, brain distribution and differential effects on the secretion of gonadotropins and growth hormone. Journal of Neuroendocrinology 28: 10.1111/jne.12377. 2016.

Bach, N.C.; Natale, G.S.; Somoza, G.M. & Ronco, A.E. Effects on growth, development and abnormalities induced by a glyphosate commercial formulation and its active ingredient on two developmental stages of the South-American common frog, Leptodactylus latrans. Environmental Science and Pollution Research 23: 23959-23971. 2016.

Gárriz, A.; Del Fresno, O.S. & Miranda, L.A. Effects of E₂ and/or EE₂ environmental concentrations on the Brain-Pituitary-Gonadal axis of pejerrey fish (Odontesthes bonariensis). Ecotoxicology and Environmental Safety 144: 45-53. 2017

Chalde, T. & Miranda, L.A. Ontogeny of hypophyseal-thyroid axis during temperature sex determination / differentiation period in pejerrey Odontesthes bonariensis. Journal of Fish Biology 91: 818-834. 2017.

Tovar Bohórquez, M.O.; Mechaly, A.S.; Hughes, L.C.; Campanella, D.; Ortí, G.; Canosa, L.F. & Somoza. G.M. Kisspeptin system in pejerrey fish (Odontesthes bonariensis). Characterization and gene expression pattern during early developmental stages. Comparative Biochemistry and Physiology 204A: 146-156. 2017.

Ramallo, M.R.; Morandini, L.; Birba, A.; Somoza, G.M. & Pandolfi, M. From molecule to behavior: brain aromatase (cyp19a1b) characterization, expression analysis and its relation with social status and male agonistic behavior in a Neotropical cichlid fish. Hormones and Behavior 89: 176-188. 2017.

Elisio, M.; Colonello, J.; Cortés, F.; Jaureguizar, A.J.; Somoza, G.M. & Macchi, G.J. Aggregations and reproductive events of the narrownose smooth hound shark, Mustelus schmitti, in relation to temperature and depth in coastal waters of the southwestern Atlantic Ocean (38-42° S). Marine and Freshwater Research 68: 732-742. 2017.

González, A.; Fernandino, J.I.; Hammond, G.L. & Somoza, G.M. Sex hormone binding globulin: Expression throughout early development and adult pejerrey fish, Odontesthes bonariensis. General and Comparative Endocrinology 247: 205-214. 2017.

Somoza, G.M. & Carriquiriborde, P. Environmental toxicology and chemistry in Latin America. Environmental Toxicology and Chemistry 7: 1715. 2017.

Young, B.; López, G.C.; Crespo, D.; Cristos, D.; Somoza, G.M. & Carriquiriborde, P. Intersex and liver alterations induced by long-term sublethal 25 exposure to 17α-ethinylestradiol in adult male Cnesterodon decemmaculatus (Pisces, Poeciliidae). Environmental Toxicology and Chemistry 7: 1738-1745. 2017.

Corchuelo, S.; Martinez, E.R.; Butzge, A.J.; Doretto, L.B.; Ricci, J.M.; Valentin, F.N.; Nakaghi, L.S. & Somoza, G.M.; Nóbrega, R.H. Gnrh/Gnih system in the olfacto-retinal system and ovary during zebrafish ovarian maturation. Molecular and Cellular Endocrinology 450: 1-13. 2017.

Hughes, L.C.; Somoza, G.M.; Nguyen, B.; Bernot, J.P.; González-Castro, M.; Díaz de Astarloa, J.M. & Ortí, G. Transcriptomic divergence and candidate genes for marine-to-freshwater transitions in the South American silverside fishes Odontesthes argentinensis and O. bonariensis. Ecology and Evolution 7: 5258-5268. 2017.

Cabrera, M.B.; Bogan, S.; Posadas, P.; Somoza, G.M.; Montoya-Burgos, J.I. & Cardoso, Y. Risks associated with introduction of poeciliids for control of mosquito larvae: first record of the non-native Gambusia holbrooki in Argentina. Journal of Fish Biology 91: 704-710. 2017.

Ramallo, M.R.; Honji, R.M.; Morandini, L.; Birba, A.; Varela, M.L.; Genovese, G.; Moreira, R.G.; Somoza, G.M. & Pandolfi, M. A game of two? Gene expression analysis of brain (cyp19a1b) and gonadal (cyp19a1a) aromatase in females of a Neotropical cichlid fish through the parental care period and removal of the offspring. General and Comparative Endocrinology 252: 119-129. 2017.

Tovar-Bohórquez, M.O.; Mechaly, A.S.; Elisio, M.; Chalde, T.; Canosa, L.F.; Miranda, L.A. & Somoza, G.M. Kisspeptins and their receptors in the brain-pituitary-gonadal axis of Odonthestes bonariensis: Their relationship with gametogenesis along the reproductive cycle. General and Comparative Endocrinology 252: 209-218. 2017.

Pérez Sirkin, D.I.; Lafont, A.G.; Kamech, N.; Somoza, G.M.; Vissio, P.G. & Dufour, S. Conservation of three-dimensional Helix-Loop-Helix structure through the vertebrate lineage reopens the cold case of Gonadotropin-Releasing Hormone Associated Peptide. Frontiers in Endocrinology 8: 207. 2017.

Elisio, M.; Vera C. & Miranda L.A. Interannual variability pattern of water temperature in a shallow lake driven by climate changes associated with ENSO and PDO phenomena. Implications on fish reproduction. Environmental Fish Biology 101: 653–666.

Scaia, M.F.; Morandini, L.; Noguera, C.A.; Ramallo, M.R.; Somoza, G.M. & Pandolfi, M. Fighting cichlids: dynamic of intrasexual aggression in dyadic agonistic encounters. Behavioural Processes 147: 61-69. 2018.

Bach, N.C.; Marino, D.J.G.; Natale, G.S. & Somoza, G.M. Effects of Glyphosate and its commercial formulation, Roundup® Ultramax, on liver histology of tadpoles of the Neotropical frog, Leptodactylus latrans (Amphibia: Anura). Chemosphere 202: 289-297. 2018.

Scaia, M.F.; Morandini, L.; Noguera, C.A.; Trudeau, V.L.; Somoza, G.M. & Pandolfi, M. Can estrogens be considered as key elements of the challenge hypothesis? The case of intrasexual agression in a cichlid fish. Physiology and Behavior 194: 481-490. 2018.

Mechaly, A.S.; Tovar Bohórquez, M.O.; Mechaly, A.E.; Suku, E.; Pérez, M.R.; Giorgetti, A.; Ortí, G.; Viñas, J. & Somoza, G.M. Evidences of alternative splicing as a regulatory mechanism for Kissr2 in pejerrey fish. Frontiers in Endocrinology 9: 604. 2018.

Petracci, P.F.; Burgos, J.M.; López, G.C.; Delhey, K.; Carrizo, M.; Sarria, R.; Sotelo, M.; Somoza, G.M. & La Sala, L.F. Field sexing Olrog’s gull (Larus atlanticus) using morphometry. Waterbirds. En prensa.

Di Yorio, M.P.; Pérez Sirkin, D.I.; Muñoz-Cueto, J.A.; Delgadin, T.H.; Tsutsui, K.; Somoza, G.M. & Vissio, P.G. Morphological relationship between GnIH and GnRH neurons in the brain of the Neotropical cichlid fish Cichlasoma dimerus. General and Comparative Endocrinology. En prensa.

Gárriz, A.; del Fresno, P.S.; Carriquiriborde, P. & Miranda, L.A. Effects of heavy metals identified in Chascomús shallow lake on the endocrine-reproductive axis of pejerrey fish (Odontesthes bonariensis). General and Comparative Endocrinology. En prensa.

Awruch, C.A.; Somoza, G.M. & Baldock, C. Chondrichthyan research in South America: endocrinology overview and research trends over 50 years (1967-2016) compared to the rest of the world. General and Comparative Endocrinology. En prensa.

González, A.; Fernandino, J.I.; Elisio, M.; Chalde, T.; Miranda, L.A., Hammond, G.L. & Somoza, G.M. Sex Hormone Binding Globulin during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis). General and Comparative Endocrinology. En prensa.