El laboratorio fue establecido en el año 2001. Si bien estudiamos fundamentalmente la fisiología de peces y la acuicultura del pejerrey, trabajamos también, con un enfoque comparativo, en fisiología de la reproducción y diferenciación sexual en otros grupos de vertebrados.

Nuestro trabajo no sólo se realiza en laboratorio sino también con un enfoque ecofisiológico estudiando reproducción en peces en su medio natural y el efecto de estresores ambientales de origen natural y antrópico.

Gonzalez A, Elisio M, Suarez J, Vega AG, Ricci E, Aristizabal EO, Miranda LA, Hirt-Chabbert JA. Influences of temperature variations on the reproductive activity of red porgy (Pagrus pagrus). Aquaculture 609, 742870. 2025. https://doi.org/10.1016/j.aquaculture.2025.742870

Mechaly AS, Elizur A, Escobar-Aguirre S, Hirt-Chabbert J, Inohuye Rivera RB, Knibb W, Nocillado J, Pérez-Urbiola JC, Premachandra HKA, Somoza GM, Tovar-Ramírez D, Wang B. Advances in reproduction, nutrition and disease research in the yellowtail kingfish (Seriola lalandi) aquaculture. Reviews in Aquaculture 17, e70034. 2025. https://doi.org/10.1111/raq.70034

Menéndez‐Helman RJ, Gárriz A, Ríos de Molina MC, Miranda LA. Impact of glyphosate herbicide exposure on sperm motility, fertilization, and embryo‐larval survival of pejerrey fsh (Odontesthes bonariensis). Environmental Science and Pollution Research. En prensa. https://doi.org/10.1007/s11356-025-35936-0

Somoza GM, Trudeau V. Sex hormones and life histories: An evolutionary perspective. Molecular and Cellular Endocrinology 595, 112369. 2025. https://doi.org/10.1016/j.mce.2024.112369

Torres Martínez N, Cristo D, Castillo AA, Berasain G, Carriquiriborde P. Herbicides in Argentine Pampas Shallow Lakes and Frequency of Testicular Lesions in the Pejerrey Fish (Odontesthes bonariensis). Bulletin of Environmental Contamination and Toxicology 115, 14. 2025. https://doi.org/10.1007/s00128-025-04086-x

Torres-Martínez A, Mancini M , Grosman F, Somoza GM, Strüssmann CA. Pejerrey (Odontesthes bonariensis) under siege: main infectious diseases and their role in aquaculture and wild populations amidst environmental change. Journal of Fish Diseases 48:e14064. 2025. https://doi.org/10.1111/jfd.14064

Berasain GE, Maraños ME, Velasco CAM, Padín DA, Mir FC, Miranda LA, Colautti DC. Crecimiento del pejerrey, Odontesthes bonariensis (Valenciennes, 1835), en cultivo y en poblaciones silvestres: un meta-análisis. Biología Acuática 42. 2024. https://doi.org/10.24215/16684869e039

Miranda LA, Rodrigues de Freitas T, Rodrigues Ferreira Machado M, Santos Marques L. Chapter in “Cryobiology for South American Neotropical fish species”. Embryos and Ovarian Tissues of South American Neotropical Fish. Edit: Strei Jr Dp, Zhang T, Paredes E. Science Publishers 8, 170-182. 2024. https://doi.org/10.1201/9781003269441

Paez WL, Somoza GM, Macchi J, Elisio M. The potential influence of photoperiod and temperature on the male reproductive physiology of the narrownose smooth hound shark, Mustelus schmitti. Marine Biology 171, 209. 2024. https://doi.org/10.1007/s00227-024-04537-9

Quesada CG, Miranda LA. Efects of hypoxia on the reproductive endocrine axis of the pejerrey (Odontesthes bonariensis). Fish Physiology and Biochemistry 50, 2505-2517. 2024.  https://doi.org/10.1007/s10695-024-01401-x

Rabuffetti G, Brola J, Pérez D, Somoza GM, Carriquiriborde P. EROD activity in the native fish Cnesterodon decemmaculatus as a biomarker for assessing aquatic pollution by AhR agonist chemicals within the Rio de la Plata Basin. Science of the Total Environment 947,  174721. 2024. https://doi.org/10.1016/j.scitotenv.2024.174721

Sueiro MC, Awruch CA, Somoza GM, Svagelj W, Palacios MG. Links between reproduction and immunity in two sympatric wild marine fishes. Comparative Biochemistry and Physiology, Part A 287, 111538. 2024. https://doi.org/10.1016/j.cbpa.2023.111538

Torres-Martínez A, Hattori RS, Fernandino JI, Somoza GM, Hung SD, Masuda Y, Yamamoto Y, Strüssmann CA. Temperature- and genotype-dependent stressresponse and activation of the hypothalamus-pituitary-interrenal axis during temperatureinduced sex reversal in pejerrey Odontesthes bonariensis, a species with genotypic and environmental sex determination. Molecular and Cellular Endocrinology 582, 112114. 2024. https://doi.org/10.1016/j.mce.2023.112114

Trudeau VL, Somoza GM. Chapter in “Encyclopedia of Reproduction  “Reproduction in Osteichthyes”. Editor Michael K. Skinner. Academic Press 560–566. 2024. https://doi.org/10.1016/B978-0-443-21477-6.00050-X 

Viana S, Petean FF, Soares K. Chondrichthyan systematics in Brazil depicted: historical overview, research trends and future perspectives. Neotropical Ichthyology 22. 3. 2024. https://doi.org/10.1590/1982-0224-2024-0011

Carriquiriborde P, Fernandino JI, López GC, de San Benito E, Gutierrez-Villagómez JN, Cristos D, Trudeau VL, Somoza GM. Atrazine alters early sexual development of the South American silverside, Odontesthes bonariensis. Aquatic Toxicology 254,  106366. 2023 https://doi.org/10.1016/j.aquatox.2022.106366

del Fresno PS, García de Souza JR, Colautti DC, Yamamoto Y, Yokota M, Strüssmann CA, Miranda LA. Sex reversal of pejerrey (odontesthes bonariensis), a species with temperature-dependent sex determination, in a seminatural environment. Journal Of Fish Biology 102, 75-82. 2023 https://doi.org/10.1111/jfb.15241

Quesada CG, Herdman J, Berasain GE, Miranda LA. Infuence of sewage discharge on dissolved oxygen concentration and fsh diversity in the Girado stream and Chascomús lake. Environmental Monitoring and Assessment 195, 1433. 2023. https://doi.org/10.1007/s10661-023-12070-3

Scaia MF, Trudeau VL, Somoza GM, Pandolfi M. Fighting cichlids: an integrated multimodal analysis to understand female and male aggression in Cichlasoma dimerus. Hormones and Behavior 148, 105301. 2023. https://doi.org/10.1016/j.yhbeh.2022.105301

Torres-Martínez A, Hattori RS, Fernandino JI, Somoza MG, Hung SD, Yamamoto Y, Strüssmann CA. Temperature- and genotype-dependent stress response and activation of the hypothalamus-pituitary-interrenal axis during temperature-induced sex reversal in pejerrey Odontesthes bonariensis, a species with genotypic and environmental sex determination. Molecular and Celular Endocrinology 582, 112114. 2024. doi:10.1016/j.mce.2023.112114

Berasain GE, Velasco CAM, Miranda LA. Actividades comerciales y recreativas en la Laguna de Chascomús. En “Laguna de Chascomús: Aportes de la Ciencia para su mejor conocimiento Editado por Berasain GE, Miranda LA. Ministerio de Desarrollo Agrario de la Provincia de Buenos Aires, La Plata, Argentina. pp. 164-172. 2022.

Berasain GE, Velasco CAM, Miranda LA. Las Hidrófitas de la Laguna de Chascomús. En “Laguna de Chascomús: Aportes de la Ciencia para su mejor conocimiento”. Editado por Berasain GE, Miranda LA.   Ministerio de Desarrollo Agrario de la Provincia de Buenos Aires, La Plata, Argentina pp. 95-104. 2022.

del Fresno P, Collautti DC, Berasain GE, Miranda LA. Gonadal development in a landlocked population of pejerrey fish Odontesthes argentinensis during spawning season in relation to sex steroids and water temperature. New Zealand Journal of Marine and Freshwater Research  56, 667–681. 2022. https://doi.org/10.1080/00288330.2021.1947328

García I, García de Souza J, Plaul SE, Miranda LA, Colautti D. Effect of photoperiod and temperature on ovarian maturation in the small characid fish Cheirodon interruptus. Journal of Applied Aquaculture. En prensa. https://doi.org/10.1080/10454438.2022.2047867

Miranda LA, Colautti DC, Berasain GE, Strüssmann CA. Variación térmica de la Laguna de Chascomús. En “Laguna Chascomús: Aportes de la Ciencia para su mejor conocimiento”. Editado por Berasain GE, Miranda LA.   Ministerio de Desarrollo Agrario de la Provincia de Buenos Aires, La Plata, Argentina. pp. 53-63. 2022.

Miranda LA, del Fresno PS, Berasain GE. Reproducción, épocas de desove y abundancia larval del pejerrey Odontesthes bonariensis en la laguna de Chascomús. En “Laguna de Chascomús: Aportes de la Ciencia para su mejor conocimiento” Editado por Berasain GE, Miranda LA. Ministerio de Desarrollo Agrario de la Provincia de Buenos Aires, La Plata, Argentina pp. 135-144. 2022.

Miranda LA,  Somoza GM.  Effects of anthropic pollutants identified in Pampas lakes on the development and reproduction of pejerrey fish Odontesthes bonariensis. Frontiers in Physiology 13, 939986. 2022. https://doi.org/10.3389/fphys.2022.939986

Sueiro MC, Palacios MG, Trudeau VL, Somoza GM, Awruch CA. Anthropogenic impact on the reproductive health of two wild Patagonian fish species with differing reproductive strategies. Science of the Total Environment  838, 155862. 2022. https://doi.org/10.1016/j.scitotenv.2022.155862

Wang B, Mechaly AS, Somoza GM. Overview and new insights into the diversity, evolution, role, and regulation of kisspeptins and their receptors in teleost fish. Frontiers in Endocrinology 13, 862614. 2022. https://doi.org/10.3389/fendo.2022.862614

Briñóccoli YF, Jardim de Queiroz L, Bogan S, Paracampo A, Posadas PE, Somoza GM, Montoya-Burgos JI, Cardoso YP. Processes that drive the population structuring of Jenynsia lineata (Cyprinidontiformes, Anablepidae) in the La Plata Basin. Ecology and Evolution 11, 6119-6132. 2021. https://doi.org/10.1002/ece3.7427

del Fresno P, Collautti DC, Berasain GE, Miranda LA. Comparative analysis of pejerrey fish (Odontesthes bonariensis) gonadal development during two consecutive spawning seasons in relation to sex steroids and temperature variation in Cochicó Lake (Pampas Region, Argentina). Turkish Journal Fisheries and Aquatic Science 23, 347-355. https://doi.org/10.4194/1303-2712-v21_7_03

del Fresno PS, Colautti DC, Berasain GE, Miranda LA. Gonadal development in pejerrey (Odontesthes bonariensis) during spawning season in relation with sex steroids and temperature variation in Gómez lake (Pampas region, Argentina). Anais da Academia Brasileira de Ciências 93, e20190795.2021. https://doi.org/10.1590/0001-3765202120190795

Lo Nostro FL, Somoza GM. Disrupción Endócrina. En “Principios de Ecotoxicología”. Editado por Carriquiriborde, P. Editorial de la Universidad Nacional de La Plata (EDULP), Argentina. pp. 184-190. 2021. http://sedici.unlp.edu.ar/handle/10915/118183

Macoretta CL, Miranda LA. Cooling of siamese fighting fish Betta splendens (Teleostei, Osphronemidae) embryos at low temperatures. Cryobiology 101, 78-86. 2021. https://doi.org/10.1016/j.cryobiol.2021.05.005

Martins AWS, Silveira TLR, Remião MH, Borges Domíngues W, Dellagostin  EN, Varela Jr AS, Corcini CD, Costa PG, Bianchini A, Somoza GM, Robaldo RB, Campos VF. Acute exposition to Roundup Transorb® induces systemic oxidative stress and alterations in the expression of newly sequenced genes in silverside fish (Odontesthes humensis). Environmental Science and Pollution Research. 28, 65127–65139. 2021. https://doi.org/10.1007/s11356-021-15239-w

Strüssmann CA, Yamamoto Y, Hattori RS, Fernandino JI, Somoza GM. Where the ends meet: an overview of sex determination in atheriniform fishes. Sexual Development. On-line. https://doi.org/10.1159/000515191

Svagelj WS, Gómez-Laich A, Pérez MR, Somoza GM, Quintana F. Sex-specific environmental sensitivity on the postnatal growth of a sexually size-dimorphic seabird. IBIS 163, 1032-1044. 2021. https://doi.org/10.1111/ibi.12920

Vissio PG, Di Yorio MP, Pérez-Sirkin DI, Somoza GM, Tsutsui K, Sallemi JE.Developmental aspects of hypothalamic-pituitary network related to reproduction in teleost fish. Frontiers in Neuroendocrinology 63, 100948. 2021. https://doi.org/10.1016/j.yfrne.2021.100948

Chalde T, Miranda LA. Characterization of the quality of the gametes and sex steroid levels during spring and summer spawning events in pejerrey Odontesthes bonariensis reared under natural conditions of temperature and photoperiod. Aquac Res. 51: 1706-1711. 2020. https://doi.org/10.1111/are.14517

Colautti DC, Miranda LA, Gonzalez-Castro M, Villanova V, Strüssmann CA, Mancini M, Maiztegui, T, Berasain GE, Hattori R, Grosman F, Sanzano P, Lozano I, Vegh SL, Salinas V, Del Ponti O, del Fresno P, Minotti P, Yamamoto Y, Baigún CRM. Evidence of a landlocked reproducing population of the marine pejerrey Odontesthes argentinensis (Actinopterygii; Atherinopsidae). J. Fish Biol. 96: 202-216. 2020. https://doi.org/10.1111/jfb.14207 

Garriz A, Miranda LA. Effects of metals on sperm quality, fertilization and hatching rates, and embryo and larval survival of pejerrey fish (Odontesthes bonariensis). Ecotoxicology En prensa. https://doi.org/10.1007/s10646-020-02245-w

González A, Kroll KJ, Silva-Sánchez C, Carriquiriborde P, Fernandino JI, Denslow ND, Somoza GM. Steroid hormones and estrogenic activity in the wastewater outfall and receiving waters of the Chascomús chained shallow lakes system (Argentina). Sci Total Environ 743: 140401. 2020.  https://doi.org/10.1016/j.scitotenv.2020.140401

Hughes LC, Cardoso YP, Sommer JA, Cifuentes R, Cuello M, Somoza GM, González-Castro M, Malabarba LR, Cussac V, Habit EM, Betancur-R R, Ortí. Biogeography, habitat transitions and hybridization in a radiation of South American silverside fishes revealed by mitochondrial and genomic RAD data. Mol Ecol. 29: 738-751. https://doi.org/10.1111/mec.15350

Macoretta CL, Miranda LA. Cooling of pejerrey Odontesthes bonariensis (Teleostei, Atherinidae) embryos at sub-zero temperatures. Theriogenology 149, 123-130. 2020. https://doi.org/10.1016/j.theriogenology.2020.03.027

Maldonado L, Tempesti TC, Somoza GM, Peluc SI, Valdez DJ. Reproductive aspects of the Eared Dove: an exception to the classic reproduction model in birds? Zoology 140: 125769. 2020. https://doi.org/10.1016/j.zool.2020.125769

Menéndez-Helman RJ, Miranda LA,  Salibián A, Dos Santos Afonso M.   Effects on ultrastructure, composition and specific surface area of the gills of Odontesthes bonariensis under subchronic glyphosate-based herbicide exposure. Bulletin of Environmental Contamination and Toxicology 105, 835-840. 2020. https://doi.org/10.1007/s00128-020-03031-4

Pérez-Sirkin DI, Solovyev M, Delgadin TH, Herdman JE, Miranda LA, Somoza GM, Vissio PG, Gisbert E. Digestive enzyme activities during pejerrey (Odontesthes bonariensis) ontogeny. Aquaculture 524, 735151. 2020. https://doi.org/10.1016/j.aquaculture.2020.735151

Somoza, G.M. El eje hipotálamo-hipofisario en los mamíferos. Las hormonas hipotalámicas relacionadas con el control de las gonadotropinas hipofisarias. En “Reproducción de los animales domésticos”. Editado por Ungerfeld, R. Grupo Editorial Asís. Zaragoza, España. pp. 8-11. 2020.

Somoza GM, Mechaly AS, Trudeau VL. Kisspeptin and GnRH interactions in the reproductive brain of teleosts. Gen Comp Endocrinol 298, 113568. 2020. https://doi.org/10.1016/j.ygcen.2020.113568

Trudeau VL, Somoza GM. Multimodal hypothalamo-hypophysial communication in the vertebrates. Gen Comp Endocrinol. 293: 113475. 2020. https://doi.org/10.1016/j.ygcen.2020.113475

Young BJ, Cristos DS, Crespo DC, Somoza GM, Carriquiriborde P. Effects of 17α-ethinylestradiol on sex ratio, gonadal histology and perianal hyperpigmentation of Cnesterodon decemmaculatus (Pisces, Poeciliidae) during a full-lifecycle exposure. Ecotoxicology and Environmental Safety 205: 111176. 2020. https://doi.org/10.1016/j.ecoenv.2020.111176

Awruch CA, Somoza GM, Baldock C. Chondrichthyan research in South America: Endocrinology overview and research trends over 50 years (1967–2016) compared to the rest of the world. Gen Comp Endocrinol. 273: 118-133. 2019. https://doi.org/10.1016/j.ygcen.2018.06.005

Castañeda Cortés DC, Arias Padilla LF, Langlois VS, Somoza GM, Fernandino JI. The central nervous system acts as a transducer of stress-induced masculinization through corticotropin-releasing hormone B. Development. 146: dev172866. 2019. https://doi.org/10.1242/dev.172866

Colautti D, Miranda LA, Gonzalez‐Castro M, Villanova GV, Strüssmann CA, Mancini M, Maiztegui T, Berasain GE, Hattori RS, Grosman F, Sanzano S, Lozano I, Llamazares Vegh S, Salinas V, O. Del Ponti P, del Fresno P., Minotti P, Yamamoto Y, Baigún C. Evidence of a landlocked reproducing population of the marine pejerrey Odontesthes argentinensis (Actinopterygii; Atherinopsidae). J Fish Biol. En prensa. https://doi.org/10.1111/jfb.14207

Di Yorio MP, Muñoz-Cueto JA, Paullada-Salmerón JA, Somoza GM, Tsutsui K, Vissio PG. The Gonadotropin-Inhibitory Hormone: What we know and what we still have to learn from fish. Front Endocrinol (Lausanne). 10: 78. 2019. https://doi.org/10.3389/fendo.2019.00078

Di Yorio MP, Pérez Sirkin DI, Muñoz-Cueto JA, Delgadin TH, Tsutsui K, Somoza GM, Vissio PG. Morphological relationship between GnIH and GnRH neurons in the brain of the Neotropical cichlid fish Cichlasoma dimerus. Gen Comp Endocrinol. 2019. 273: 144-151. 2019. https://doi.org/10.1016/j.ygcen.2018.06.010

Elisio M, Awruch CA, Massa AM, Macchi GJ, Somoza GM. Effects of temperature on the reproductive physiology of female elasmobranchs: The case of the narrownose smooth-hound shark (Mustelus schmitti). Gen Comp Endocrinol. 284: 113242. 2019. https://doi.org/10.1016/j.ygcen.2019.113242.

García ID, Plaul SE, Torres D, Del Fresno PS, Miranda LA, Colautti DC. Effect of photoperiod on ovarian maturation in Cheirodon interruptus (Teleostei: Characidae). Braz J Biol. 79: 669-677. 2019. https://doi.org/10.1590/1519-6984.188607

Gárriz A, Del Fresno PS, Carriquiriborde P, Miranda LA. Effects of heavy metals identified in Chascomús shallow lake on the endocrine-reproductive axis of pejerrey fish (Odontesthes bonariensis). Gen Comp Endocrinol. 273: 152-162. 2019. https://doi.org/10.1016/j.ygcen.2018.06.013

González A, Fernandino JI, Elisio M, Chalde T, Miranda LA, Hammond GL, Somoza GM. Sex hormone binding globulin during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis). Gen Comp Endocrinol. 272: 52-56. 2019. https://doi.org/10.1016/j.ygcen.2018.11.010

Hattori RS, Somoza GM, Fernandino JI, Colautti DC, Miyoshi K, Gong Z, Yamamoto Y, Strüssmann CA. The duplicated Y-specific amhy gene is conserved and linked to maleness in silversides of the genus Odontesthes. Genes (Basel). 10: 679. 2019. https://doi.org/10.3390/genes10090679

Miranda LA, Del Fresno P. Influencia de la temperatura del agua sobre la época de desove del pejerrey. En: “Destino: La Barrancosa. Una invitación a conocer las lagunas pampeanas”. Editado por: Grosman F, Sanzano P, Bertora, A. Universidad del Centro de la Provincia de Buenos Aires. Pp: 212-223. 2019. ISBN 978-950-658-495-5

Morandini L, Ramallo MR, Scaia MF, Höcht C, Somoza GM, Pandolfi M. Dietary L-tryptophan modulates agonistic behavior and brain serotonin in male dyadic contests of a cichlid fish. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 205: 867-880. 2019. https://doi.org/10.1007/s00359-019-01373-x

Peixoto MJ, Ferraz R, Magnoni LJ, Pereira R, Gonçalves JF, Calduch-Giner J, Pérez-Sánchez J, Ozório ROA. Protective effects of seaweed supplemented diet on antioxidant and immune responses in European seabass (Dicentrarchus labrax) subjected to bacterial infection. Sci Rep. 9: 16134. 2019. https://doi.org/10.1038/s41598-019-52693-6

Petracci PF, Burgos JM, López GC, Delhey K, Carrizo M, Sarria R, Sotelo M, Somoza GM, La Sala LF. Field sexing Olrog’s gull (Larus atlanticus) using morphometry. Waterbirds. 41: 411-416. 2019. https://doi.org/10.1675/063.041.0404

Somoza GM, Nóbrega RH. Endocrinology of neotropical vertebrates. Gen Comp Endocrinol. 273:1-2. 2019. https://doi.org/10.1016/j.ygcen.2019.01.008